Fosamprenavir vs Lopinavir

Interacting Drugs
Fosamprenavir
vs
Lopinavir
Security Level
Moderate, Consider therapy modification
Mechanism
Lopinavir: Fosamprenavir may decrease the serum concentration of Lopinavir. Specifically, amprenavir (the active metabolite of fosamprenavir) may decrease the serum concentration of lopinavir.
Management
Lopinavir/ritonavir should not be used as a once daily regimen when used together with fosamprenavir. The use of ritonavir-boosted fosamprenavir with lopinavir/ritonavir may negate this interaction.

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Other Interactions of Fosamprenavir

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Other Interactions of Lopinavir

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