Enalapril vs Sodium Phosphates

Interacting Drugs
Enalapril
vs
Sodium Phosphates
Security Level
Moderate, Consider therapy modification
Mechanism
Sodium Phosphates: ACE Inhibitors may enhance the nephrotoxic effect of Sodium Phosphates. Specifically, the risk of acute phosphate nephropathy may be enhanced.
Management
Consider avoiding this combination by temporarily suspending treatment with ACEIs, or seeking alternatives to oral sodium phosphate bowel preparation. If the combination cannot be avoided, maintain adequate hydration and monitor renal function closely.

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