Doxercalciferol vs Bile Acid Sequestrants

Interacting Drugs
Doxercalciferol
vs
Bile Acid Sequestrants
Security Level
Moderate, Consider therapy modification
Mechanism
Bile Acid Sequestrants: May decrease the serum concentration of Vitamin D Analogs. More specifically, bile acid sequestrants may impair absorption of Vitamin D Analogs.
Management
Avoid concomitant administration of vitamin D analogs and bile acid sequestrants (e.g., cholestyramine). Separate administration of these agents by several hours to minimize the potential risk of interaction. Monitor plasma calcium concentrations.

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