Diltiazem vs Protease Inhibitors

Interacting Drugs
Diltiazem
vs
Protease Inhibitors
Security Level
Moderate, Consider therapy modification
Mechanism
Protease Inhibitors: May decrease the metabolism of Calcium Channel Blockers (Nondihydropyridine). Increased serum concentrations of the calcium channel blocker may increase risk of AV nodal blockade.
Management
Avoid concurrent use when possible. If this combination is used, monitor for evidence of toxicity. The manufacturer of atazanavir recommends a 50% dose reduction for diltiazem be considered. Use of ritonavir with bepridil is contraindicated.

Subscribe for latest updates

Subscribe to our e-mail newsletter to receive updates.

No comments yet.

Post Review about Diltiazem vs Protease Inhibitors