Diclofenac and misoprostol vs CycloSPORINE (Systemic)

Interacting Drugs
Diclofenac and misoprostol
vs
CycloSPORINE (Systemic)
Security Level
Moderate, Consider therapy modification
Mechanism
CycloSPORINE (Systemic): Nonsteroidal Anti-Inflammatory Agents may enhance the nephrotoxic effect of CycloSPORINE (Systemic). Nonsteroidal Anti-Inflammatory Agents may increase the serum concentration of CycloSPORINE (Systemic).
Management
Consider therapy modification

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