Darunavir vs FentaNYL

Interacting Drugs
Darunavir
vs
FentaNYL
Security Level
Moderate, Consider therapy modification
Mechanism
FentaNYL: CYP3A4 Inhibitors (Strong) may increase the serum concentration of FentaNYL.
Management
Monitor patients extra closely for several days following initiation of the combination, and fentanyl dosage reductions should be made as appropriate.

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