Chlorthalidone vs Dofetilide

Interacting Drugs
Chlorthalidone
vs
Dofetilide
Security Level
Major, Avoid combination
Mechanism
Dofetilide: Thiazide Diuretics may enhance the QTc-prolonging effect of Dofetilide. Thiazide Diuretics may increase the serum concentration of Dofetilide.
Management
Avoid combination

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