Boceprevir vs Vardenafil

Interacting Drugs
Boceprevir
vs
Vardenafil
Security Level
Moderate, Consider therapy modification
Mechanism
Vardenafil: CYP3A4 Inhibitors (Strong) may increase the serum concentration of Vardenafil.
Management
Limit the vardenafil dose to 2.5 mg/24-hour period when used with strong CYP3A4 inhibitors. With ritonavir limit dose to 2.5 mg/72-hour period. With lower doses of some inhibitors, a reduction to 5 mg/24-hour period may be adequate.

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Boceprevir vs Vardenafil

Interacting Drugs
Boceprevir
vs
Vardenafil
Security Level
Moderate, Consider therapy modification
Mechanism
Vardenafil: Boceprevir may increase the serum concentration of Vardenafil.
Management
Limit vardenafil maximum dose to 2.5 mg every 24 hours and monitor closely for symptoms of vardenafil toxicity (including hypotension, visual changes, syncope, and priapism) during treatment with boceprevir.

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Post Review about Boceprevir vs Vardenafil