Aluminum hydroxide, magnesium hydroxide, and simethicone vs Levothyroxine

Interacting Drugs
Aluminum hydroxide, magnesium hydroxide, and simethicone
vs
Levothyroxine
Security Level
Moderate, Consider therapy modification
Mechanism
Levothyroxine: Aluminum Hydroxide may decrease the serum concentration of Levothyroxine.
Management
Separate administration of oral levothyroxine and aluminum hydroxide by at least 4 hours.

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