Interacting Drugs |
Vinblastine vs Macrolide Antibiotics |
Security Level |
 |
Mechanism |
Macrolide Antibiotics: May increase the serum concentration of Antineoplastic Agents (Vinca Alkaloids). Macrolides may also increase the distribution of Vinca Alkaloids into certain cells and/or tissues. |
Management |
Consider an alternative to using a macrolide antibiotic when possible in order to avoid the potential for increased vinca alkaloid toxicity. Exceptions: Azithromycin; Azithromycin (Systemic); Fidaxomicin (Systemic). |
Vinblastine vs Macrolide Antibiotics
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Other Interactions of Vinblastine
Other Interactions of Macrolide Antibiotics
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