Trazodone vs Linagliptin

Interacting Drugs
Trazodone
vs
Linagliptin
Security Level
Moderate, Consider therapy modification
Mechanism
Linagliptin: P-glycoprotein/ABCB1 Inducers may decrease the serum concentration of Linagliptin.
Management
Strongly consider using an alternative to any strong P-glycoprotein inducer in patients who are being treated with linagliptin. If this combination is used, monitor patients closely for evidence of reduced linagliptin effectiveness.

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