Topical cocaine vs TraMADol

Interacting Drugs
Topical cocaine
vs
TraMADol
Security Level
Minor, Monitor Therapy
Mechanism
TraMADol: CYP2D6 Inhibitors (Strong) may diminish the therapeutic effect of TraMADol. These CYP2D6 inhibitors may prevent the metabolic conversion of tramadol to its active metabolite that accounts for much of its opioid-like effects.
Management
Monitor therapy

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