Topical cocaine vs Iloperidone

Interacting Drugs
Topical cocaine
vs
Iloperidone
Security Level
Moderate, Consider therapy modification
Mechanism
Iloperidone: CYP2D6 Inhibitors (Strong) may increase serum concentrations of the active metabolite(s) of Iloperidone. Specifically, concentrations of the metabolite P88 may be increased. CYP2D6 Inhibitors (Strong) may decrease serum concentrations of the active metabolite(s) of Iloperidone. Specifically, concentrations of the metabolite P95 may be decreased. CYP2D6 Inhibitors (Strong) may increase the serum concentration of Iloperidone.
Management
Reduce iloperidone dose by half when administered with a strong CYP2D6 inhibitor.

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Other Interactions of Topical cocaine

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Other Interactions of Iloperidone

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