Temsirolimus vs CycloSPORINE

Interacting Drugs
Temsirolimus
vs
CycloSPORINE
Security Level
Moderate, Consider therapy modification
Mechanism
CycloSPORINE: Temsirolimus may enhance the adverse/toxic effect of CycloSPORINE. An increased risk of calcineurin inhibitor-induced hemolytic uremic syndrome/thrombotic thrombocytopenic purpura/thrombotic microangiopathy (HUS/TTP/TMA) has been described with concomitant sirolimus use.
Management
Consider therapy modification

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Other Interactions of Temsirolimus

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Other Interactions of CycloSPORINE

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