Tacrolimus (systemic) vs Ketoconazole (Systemic)

Interacting Drugs
Tacrolimus (systemic)
Ketoconazole (Systemic)
Security Level
Moderate, Consider therapy modification
Ketoconazole (Systemic): May increase the serum concentration of Tacrolimus (Systemic).
Tacrolimus dose adjustment may be required when taken with ketoconazole due to elevated plasma concentrations of tacrolimus. Monitor tacrolimus concentrations and clinical response closely.

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