Sunitinib vs Leflunomide

Interacting Drugs
Sunitinib
vs
Leflunomide
Security Level
Moderate, Consider therapy modification
Mechanism
Leflunomide: Immunosuppressants may enhance the adverse/toxic effect of Leflunomide. Specifically, the risk for hematologic toxicity such as pancytopenia, agranulocytosis, and/or thrombocytopenia may be increased.
Management
Consider not using a leflunomide loading dose in patients receiving other immunosuppressants. Patients receiving both leflunomide and another immunosuppressant should be monitored for bone marrow suppression at least monthly.

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Other Interactions of Sunitinib

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Other Interactions of Leflunomide

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