Sufentanil vs MAO Inhibitors

Interacting Drugs
Sufentanil
vs
MAO Inhibitors
Security Level
Major, Avoid combination
Mechanism
MAO Inhibitors: Anilidopiperidine Opioids may enhance the serotonergic effect of MAO Inhibitors. This could result in serotonin syndrome.
Management
Avoid use of fentanyl (and other anilidopiperidine opioids when possible) in patients who have used a monoamine oxidase inhibitor within the past 14 days due to reports of unpredictable but severe adverse effects.

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Other Interactions of Sufentanil

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Other Interactions of MAO Inhibitors

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