Sucralfate vs Quinolone Antibiotics

Interacting Drugs
Sucralfate
vs
Quinolone Antibiotics
Security Level
Moderate, Consider therapy modification
Mechanism
Quinolone Antibiotics: Sucralfate may decrease the serum concentration of Quinolone Antibiotics.
Management
Administer oral quinolones at least 2 hours before or 6 hours after the sucralfate dose. Greater separation of doses may further lessen the risk for a significant interaction.

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