Sirolimus vs Tacrolimus (Topical)

Interacting Drugs
Sirolimus
vs
Tacrolimus (Topical)
Security Level
Moderate, Consider therapy modification
Mechanism
Tacrolimus (Topical): May enhance the adverse/toxic effect of Sirolimus. Sirolimus may enhance the adverse/toxic effect of Tacrolimus (Topical).
Management
Consider therapy modification

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Sirolimus vs Tacrolimus (Topical)

Interacting Drugs
Sirolimus
vs
Tacrolimus (Topical)
Security Level
Major, Avoid combination
Mechanism
Tacrolimus (Topical): May enhance the adverse/toxic effect of Immunosuppressants.
Management
Avoid combination

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