Sirolimus vs Ketoconazole (Systemic)

Interacting Drugs
Sirolimus
vs
Ketoconazole (Systemic)
Security Level
Moderate, Consider therapy modification
Mechanism
Ketoconazole (Systemic): May increase the serum concentration of Sirolimus.
Management
Sirolimus dose adjustments will likely be needed when starting/stopping any azole antifungal. Clinical data suggest sirolimus (adult) dose reductions of 50-90% will be needed when starting an azole antifungal, but specific guidelines are lacking.

Subscribe for latest updates

Subscribe to our e-mail newsletter to receive updates.

No comments yet.

Post Review about Sirolimus vs Ketoconazole (Systemic)