Sirolimus vs CycloSPORINE

Interacting Drugs
Sirolimus
vs
CycloSPORINE
Security Level
Moderate, Consider therapy modification
Mechanism
CycloSPORINE: Sirolimus may enhance the adverse/toxic effect of CycloSPORINE. An increased risk of calcineurin inhibitor-induced hemolytic uremic syndrome/thrombotic thrombocytopenic purpura/thrombotic microangiopathy (HUS/TTP/TMA) has been described. CycloSPORINE may increase the serum concentration of Sirolimus. This is of specific concern with cyclosporine [MODIFIED].
Management
Administer oral doses of sirolimus 4 hours after doses of cyclosporine. Monitor for toxic effects of sirolimus if used with cyclosporine.

Subscribe for latest updates

Subscribe to our e-mail newsletter to receive updates.

No comments yet.

Post Review about Sirolimus vs CycloSPORINE


Other Interactions of Sirolimus

We are Developing Our database, More results coming soon.

Other Interactions of CycloSPORINE

We are Developing Our database, More results coming soon.