Salsalate vs ACE Inhibitors

Interacting Drugs
ACE Inhibitors
Security Level
Minor, Monitor Therapy
ACE Inhibitors: Salicylates may diminish the antihypertensive effect of ACE Inhibitors. They may also diminish other beneficial pharmacodynamic effects desired for the treatment of CHF. The effects are likely dose-related. 100 mg doses aspirin appear to cause no problems, whereas 300 mg doses appear to significantly affect ACE Inhibitor efficacy.
Monitor therapy

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