Rifampin, isoniazid, and pyrazinamide vs Rifampin

Interacting Drugs
Rifampin, isoniazid, and pyrazinamide
vs
Rifampin
Security Level
Moderate, Consider therapy modification
Mechanism
Rifampin: Pyrazinamide may enhance the hepatotoxic effect of Rifampin. Severe (even fatal) liver injury has been reported in patients receiving these 2 drugs as a 2-month treatment regimen for latent TB infection.
Management
Consider therapy modification

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Other Interactions of Rifampin, isoniazid, and pyrazinamide

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Other Interactions of Rifampin

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