Interacting Drugs |
Rifampin, isoniazid, and pyrazinamide vs Pyrazinamide |
Security Level |
 |
Mechanism |
Pyrazinamide: May enhance the hepatotoxic effect of Rifampin. Severe (even fatal) liver injury has been reported in patients receiving these 2 drugs as a 2-month treatment regimen for latent TB infection. |
Management |
Consider therapy modification |
Rifampin, isoniazid, and pyrazinamide vs Pyrazinamide
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Other Interactions of Rifampin, isoniazid, and pyrazinamide
Other Interactions of Pyrazinamide
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