Rifampin and isoniazid vs Brentuximab Vedotin

Interacting Drugs
Rifampin and isoniazid
vs
Brentuximab Vedotin
Security Level
Minor, Monitor Therapy
Mechanism
Brentuximab Vedotin: CYP3A4 Inducers (Strong) may decrease the serum concentration of Brentuximab Vedotin. Specifically, concentrations of the active monomethyl auristatin E (MMAE) component may be decreased.
Management
Monitor therapy

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