Polysaccharide-iron complex and folic acid vs Levothyroxine

Interacting Drugs
Polysaccharide-iron complex and folic acid
vs
Levothyroxine
Security Level
Moderate, Consider therapy modification
Mechanism
Levothyroxine: Iron Salts may decrease the serum concentration of Levothyroxine.
Management
Separate oral administration of iron salts and levothyroxine by at least 4 hours. Separation of doses is not required with parenterally administered iron salts or levothyroxine.

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