Phenobarbital vs GuanFACINE

Interacting Drugs
Phenobarbital
vs
GuanFACINE
Security Level
Moderate, Consider therapy modification
Mechanism
GuanFACINE: CYP3A4 Inducers (Strong) may decrease the serum concentration of GuanFACINE.
Management
Consider increasing the guanfacine dose (within the labeled dosage range) when such a combination is used.

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