Ofloxacin (systemic) vs Antacids

Interacting Drugs
Ofloxacin (systemic)
vs
Antacids
Security Level
Moderate, Consider therapy modification
Mechanism
Antacids: May decrease the absorption of Quinolone Antibiotics. Of concern only with oral administration of quinolones. Exceptions: Sodium Bicarbonate.
Management
Consider therapy modification

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