Midazolam vs Antifungal Agents (Azole Derivatives, Systemic)

Interacting Drugs
Midazolam
vs
Antifungal Agents (Azole Derivatives, Systemic)
Security Level
Moderate, Consider therapy modification
Mechanism
Antifungal Agents (Azole Derivatives, Systemic): May decrease the metabolism of Benzodiazepines (metabolized by oxidation).
Management
The following combinations are specifically contraindicated: itraconazole with alprazolam, estazolam, oral midazolam, or triazolam; ketoconazole with alprazolam, estazolam, or triazolam. Consider initial dose reductions of other benzodiazepines.

Subscribe for latest updates

Subscribe to our e-mail newsletter to receive updates.

No comments yet.

Post Review about Midazolam vs Antifungal Agents (Azole Derivatives, Systemic)