Miconazole (oral) vs Ranolazine

Interacting Drugs
Miconazole (oral)
vs
Ranolazine
Security Level
Moderate, Consider therapy modification
Mechanism
Ranolazine: CYP3A4 Inhibitors (Moderate) may increase the serum concentration of Ranolazine.
Management
Limit the ranolazine adult dose to a maximum of 500 mg twice daily in patients concurrently receiving moderate CYP3A4 inhibitors (e.g., diltiazem, verapamil, erythromycin, etc.).

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