Mephobarbital vs LamoTRIgine

Interacting Drugs
Mephobarbital
vs
LamoTRIgine
Security Level
Moderate, Consider therapy modification
Mechanism
LamoTRIgine: Barbiturates may decrease the serum concentration of LamoTRIgine.
Management
See lamotrigine prescribing information for specific age-dependent dosing guidelines regarding concurrent use with a barbiturate, as well as for adjusting lamotrigine dosing if concurrent barbiturate therapy is discontinued.

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