Magnesium carbonate, calcium carbonate, and folic acid vs Ketoconazole (Systemic)

Interacting Drugs
Magnesium carbonate, calcium carbonate, and folic acid
vs
Ketoconazole (Systemic)
Security Level
Moderate, Consider therapy modification
Mechanism
Ketoconazole (Systemic): Antacids may decrease the serum concentration of Ketoconazole (Systemic).
Management
Administer oral ketoconazole at least 2 hours prior to use of any antacid product. Monitor patients closely for signs of inadequate clinical response to ketoconazole.

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