Loratadine and pseudoephedrine vs Amiodarone

Interacting Drugs
Loratadine and pseudoephedrine
vs
Amiodarone
Security Level
Moderate, Consider therapy modification
Mechanism
Amiodarone: May increase the serum concentration of Loratadine.
Management
Due to reported QT interval prolongation and Torsades de Pointes with this combination, consider an alternative to loratadine when possible.

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