Interacting Drugs |
Ketoconazole (systemic) vs Protease Inhibitors |
Security Level |
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Mechanism |
Protease Inhibitors: Antifungal Agents (Azole Derivatives, Systemic) may increase the serum concentration of Protease Inhibitors. Protease Inhibitors may increase the serum concentration of Antifungal Agents (Azole Derivatives, Systemic). |
Management |
Limit indinavir adult dose to 600 mg every 8 hours with itraconazole or ketoconazole. With ritonavir, limit ketoconazole adult dose to 200 mg/day. Limit fluconazole, itraconazole, and ketoconazole to 200 mg (adult dose) with tipranavir/ritonavir. |
Ketoconazole (systemic) vs Protease Inhibitors
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Other Interactions of Ketoconazole (systemic)
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