Ketoconazole (systemic) vs Irinotecan

Interacting Drugs
Ketoconazole (systemic)
vs
Irinotecan
Security Level
Moderate, Consider therapy modification
Mechanism
Irinotecan: Antifungal Agents (Azole Derivatives, Systemic) may enhance the adverse/toxic effect of Irinotecan.
Management
Consider therapy modification

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