Interacting Drugs |
Ketoconazole (systemic) vs HMG-CoA Reductase Inhibitors |
Security Level |
 |
Mechanism |
HMG-CoA Reductase Inhibitors: Antifungal Agents (Azole Derivatives, Systemic) may decrease the metabolism of HMG-CoA Reductase Inhibitors. |
Management |
Consider use of HMG-CoA reductase inhibitors posing the least rhabdomyolysis risk (e.g. fluva- or pravastatin), and monitor for signs/symptoms of rhabdomyolysis. Do not use keto- or itraconazole with lova- or simvastatin, or posaconazole with simvastatin. Exceptions: Fluvastatin; Pitavastatin; Rosuvastatin. |
Ketoconazole (systemic) vs HMG-CoA Reductase Inhibitors
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Other Interactions of Ketoconazole (systemic)
Other Interactions of HMG-CoA Reductase Inhibitors
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