Ketoconazole (systemic) vs Colchicine

Interacting Drugs	Ketoconazole (systemic) vs Colchicine
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Mechanism	Colchicine: P-glycoprotein/ABCB1 Inhibitors may increase the serum concentration of Colchicine. Colchicine distribution into certain tissues (e.g., brain) may also be increased.
Management	Colchicine is contraindicated in patients with impaired renal or hepatic function who are also receiving a p-glycoprotein inhibitor. In those with normal renal and hepatic function, reduce colchicine dose as directed.

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Other Interactions of Ketoconazole (systemic)

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Other Interactions of Colchicine

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Interacting Drugs	Ketoconazole (systemic) vs Colchicine
Security Level
Mechanism	Colchicine: CYP3A4 Inhibitors (Strong) may increase the serum concentration of Colchicine.
Management	Colchicine is contraindicated in patients with impaired renal or hepatic function who are also receiving a strong CYP3A4 inhibitor. In those with normal renal and hepatic function, reduce colchicine dose as directed.

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Other Interactions of Ketoconazole (systemic)

We are Developing Our database, More results coming soon.

Other Interactions of Colchicine

We are Developing Our database, More results coming soon.