Interacting Drugs |
Ketoconazole (systemic) vs Benzodiazepines (metabolized by oxidation) |
Security Level |
 |
Mechanism |
Benzodiazepines (metabolized by oxidation): Antifungal Agents (Azole Derivatives, Systemic) may decrease the metabolism of Benzodiazepines (metabolized by oxidation). |
Management |
The following combinations are specifically contraindicated: itraconazole with alprazolam, estazolam, oral midazolam, or triazolam; ketoconazole with alprazolam, estazolam, or triazolam. Consider initial dose reductions of other benzodiazepines. Exceptions: Quazepam. |
Ketoconazole (systemic) vs Benzodiazepines (metabolized by oxidation)
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Other Interactions of Ketoconazole (systemic)
Other Interactions of Benzodiazepines (metabolized by oxidation)
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