Isotretinoin vs Contraceptives (Progestins)

Interacting Drugs
Isotretinoin
vs
Contraceptives (Progestins)
Security Level
Moderate, Consider therapy modification
Mechanism
Contraceptives (Progestins): Retinoic Acid Derivatives may diminish the therapeutic effect of Contraceptives (Progestins). Retinoic Acid Derivatives may decrease the serum concentration of Contraceptives (Progestins).
Management
Two forms of effective contraception should be used in patients receiving retinoic acid derivatives. Particularly, microdosed progesterone-only preparations may be inadequately effective.

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Other Interactions of Contraceptives (Progestins)

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