Hyoscyamine, atropine, scopolamine, and phenobarbital vs Tolvaptan

Interacting Drugs
Hyoscyamine, atropine, scopolamine, and phenobarbital
vs
Tolvaptan
Security Level
Major, Avoid combination
Mechanism
Tolvaptan: CYP3A4 Inducers (Strong) may decrease the serum concentration of Tolvaptan.
Management
If concurrent use is necessary, increased doses of tolvaptan (with close monitoring for toxicity and clinical response) may be needed.

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Other Interactions of Hyoscyamine, atropine, scopolamine, and phenobarbital

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Other Interactions of Tolvaptan

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