Fosphenytoin vs Cimetidine

Interacting Drugs
Fosphenytoin
vs
Cimetidine
Security Level
Moderate, Consider therapy modification
Mechanism
Cimetidine: May enhance the adverse/toxic effect of Anticonvulsants (Hydantoin). Cimetidine may increase the serum concentration of Anticonvulsants (Hydantoin).
Management
Consider using an alternative H2-antagonist to avoid this interaction. Monitor for toxic effects of hydantoin anticonvulsants if cimetidine is initiated/dose increased.

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Other Interactions of Fosphenytoin

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Other Interactions of Cimetidine

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