Ezetimibe and simvastatin vs Eltrombopag

Interacting Drugs
Ezetimibe and simvastatin
vs
Eltrombopag
Security Level
Moderate, Consider therapy modification
Mechanism
Eltrombopag: May increase the serum concentration of OATP1B1/SLCO1B1 Substrates.
Management
According to eltrombopag prescribing information, consideration of a preventative dose reduction may be warranted.

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