Eplerenone vs CYP3A4 Inhibitors (Moderate)

Interacting Drugs
Eplerenone
vs
CYP3A4 Inhibitors (Moderate)
Security Level
Moderate, Consider therapy modification
Mechanism
CYP3A4 Inhibitors (Moderate): May increase the serum concentration of Eplerenone.
Management
A lower starting dose of eplerenone (25 mg once daily for adults) is recommended in patients with hypertension who are also taking drugs that are moderate inhibitors of CYP3A4.

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Other Interactions of Eplerenone

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Other Interactions of CYP3A4 Inhibitors (Moderate)

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