Desipramine vs Alpha-/Beta-Agonists (Direct-Acting)

Interacting Drugs
Desipramine
vs
Alpha-/Beta-Agonists (Direct-Acting)
Security Level
Moderate, Consider therapy modification
Mechanism
Alpha-/Beta-Agonists (Direct-Acting): Tricyclic Antidepressants may enhance the vasopressor effect of Alpha-/Beta-Agonists (Direct-Acting). Exceptions: Dipivefrin.
Management
Consider therapy modification

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