Darunavir vs Lapatinib

Interacting Drugs
Darunavir
vs
Lapatinib
Security Level
Major, Avoid combination
Mechanism
Lapatinib: CYP3A4 Inhibitors (Strong) may increase the serum concentration of Lapatinib.
Management
If an overlap in therapy cannot be avoided, consider reducing lapatinib dose to 500 mg/day during, and within 1 week of completing, treatment with the strong CYP3A4 inhibitor.

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Other Interactions of Darunavir

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Other Interactions of Lapatinib

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