Dapsone (topical) vs Antimalarial Agents

Interacting Drugs
Dapsone (topical)
vs
Antimalarial Agents
Security Level
Moderate, Consider therapy modification
Mechanism
Antimalarial Agents: May enhance the adverse/toxic effect of Dapsone (Topical). Specifically, the risk of hemolytic reactions may be increased.
Management
Closely monitor for signs/symptoms of hemolytic reactions with concomitant use of topical dapsone and antimalarial agents. Patients with glucose-6-phosphate dehydrogenase deficiency may be at particularly high risk for adverse hematologic effects.

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Other Interactions of Dapsone (topical)

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Other Interactions of Antimalarial Agents

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