Dabigatran vs QuiNIDine

Interacting Drugs
Dabigatran
vs
QuiNIDine
Security Level
Moderate, Consider therapy modification
Mechanism
QuiNIDine: May increase the serum concentration of Dabigatran Etexilate.
Management
Canadian (but not U.S.) prescribing information recommends dosing dabigatran 2 hours prior to quinidine, and limiting dabigatran VTE prevention dose post hip/knee replacement to 150 mg/day in patients receiving quinidine.

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