Interacting Drugs |
Dabigatran vs P-glycoprotein/ABCB1 Inhibitors |
Security Level |
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Mechanism |
P-glycoprotein/ABCB1 Inhibitors: May increase serum concentrations of the active metabolite(s) of Dabigatran Etexilate. |
Management |
Dabigatran dose reductions may be needed. According to Canadian labeling, dabigatran dose for prevention of venous thromboembolism post hip or knee replacement should be reduced to 150 mg/day in patients receiving amiodarone, verapamil, or quinidine. |
Dabigatran vs P-glycoprotein/ABCB1 Inhibitors
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Other Interactions of P-glycoprotein/ABCB1 Inhibitors
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