Cimetidine vs Erlotinib

Interacting Drugs
Cimetidine
vs
Erlotinib
Security Level
Moderate, Consider therapy modification
Mechanism
Erlotinib: H2-Antagonists may decrease the serum concentration of Erlotinib.
Management
Avoid H2-antagonists in patients receiving erlotinib when possible. If concomitant treatment cannot be avoided, erlotinib should be dosed once daily, 10 hours after and at least 2 hours before H2-antagonist dosing.

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Other Interactions of Cimetidine

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Other Interactions of Erlotinib

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