Bisoprolol and hydrochlorothiazide vs Theophylline Derivatives

Interacting Drugs
Bisoprolol and hydrochlorothiazide
vs
Theophylline Derivatives
Security Level
Minor, Monitor Therapy
Mechanism
Theophylline Derivatives: Beta-Blockers (Beta1 Selective) may diminish the bronchodilatory effect of Theophylline Derivatives.
Management
Monitor for reduced theophylline efficacy during concomitant use with any beta-blocker. Beta-1 selective agents are less likely to antagonize theophylline than nonselective agents, but selectivity may be lost at higher doses.

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Other Interactions of Theophylline Derivatives

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